Prof Conny Bonifer

Details

Role Senior Principal Research Fellow

Research area Stem Cell Medicine

Group Blood Development

Bonifer, C. Mechanistic insights into gene regulation driving normal and malignant hematopoietic development from embryonic and induced pluripotent stem cell differentiation.. Exp Hematol 105442 2026
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Nafria, M, Keane, P, Ng, ES, Stanley, EG, Elefanty, AG, Bonifer, C. RUNX1-ETO induction rapidly alters chromatin landscape and growth of a specific sub-population of hESC-derived myeloid precursor cells by interfering with RUNX1 regulation. 2026
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Derevyanko, PK, Swart, LE, Casimiro, LDM, van den Brink, L, van Oort, AT, Ashtiani, M, Zwaan, CM, Krippner-Heidenreich, A, Bonifer, C, Schiffelers, R, et al. RUNX1::RUNX1T1 Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia. 2026
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Maytum, A, Edginton-White, B, Keane, P, Cockerill, PN, Cazier, J-B, Bonifer, C. Chromatin priming elements direct tissue-specific gene activity prior to hematopoietic specification. 2026
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Kellaway, SG, Keane, P, Edginton-White, B, Kakkad, R, Kennett, E, Bonifer, C. Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories. 2026
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