Prof John Bateman
Prof John Bateman
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Available for student supervision
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s...
Formation of the human skeleton and proper bone, cartilage, joint and muscle function are determined by complex interactions between developmental signalling pathways. Genetic and acquired disorders affecting these tissues are common. The group’s research is aimed at understanding the molecular basis of these disorders to improve diagnosis and counselling, identify new therapeutic targets and test the effectiveness of new treatments to ultimately improve the quality of life for children with these debilitating conditions
Top Publications
- Yammine, KM, Abularach, SM, Kim, S-Y, Bikovtseva, AA, Lilianty, J, Butty, VL, Schiavoni, RP, Bateman, JF, Lamandé, SR, Shoulders, MD. ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis.. 2024 view publication
- Lamandé, SR, Ng, ES, Cameron, TL, Kung, LHW, Sampurno, L, Rowley, L, Lilianty, J, Patria, YN, Stenta, T, Hanssen, E, et al. Modeling human skeletal development using human pluripotent stem cells.. Proc Natl Acad Sci U S A 120(19) : e2211510120 2023 view publication
- Yeung, C-YC, Olesen, AT, Wilson, R, Lamandé, SR, Bateman, JF, Svensson, RB, Magnusson, SP, Kjaer, M. Proteome profiles of intramuscular connective tissue: influence of aging and physical training.. J Appl Physiol (1985) 134(5) : 1278 -1286 2023 view publication
- Yammine, KM, Mirda Abularach, S, Sampurno, L, Bateman, JF, Lamandé, SR, Shoulders, MD. Using CRISPR/Cas9 to generate a heterozygous COL2A1 p.R719C iPSC line (MCRIi019-A-6) model of human precocious osteoarthritis.. Stem Cell Res 67: 103020 2023 view publication
- Blank, M, McGregor, NE, Rowley, L, Kung, LHW, Crimeen-Irwin, B, Poulton, IJ, Walker, EC, Gooi, JH, Lamandé, SR, Sims, NA, et al. The effect of carbamazepine on bone structure and strength in control and osteogenesis imperfecta (Col1a2 +/p.G610C ) mice.. J Cell Mol Med 26(14) : 4021 -4031 2022 view publication
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