photo of Dr Prue Pereira

Dr Prue Pereira

Dr Prue Pereira

Details

Role Team Leader / Senior Research Officer
Research area Clinical Sciences

Contact

Available for student supervision
Dr. Pereira-Fantini is a scientist and Leader of the Molecular Lung Injury program of the Neonatal Research group (Murdoch Children’s Research Institute). Since obtaining her PhD from The University of Melbourne (2005), her career has focused on using preclinical animal models to define the injury mechanisms underlying paediatric disease. Her research focuses on using innovative methods to (1) define the cellular events underlying preterm lung injury initiation, (2) identify new treatment targets and (3) develop tests for the early detection of lung injury.

Dr Pereira-Fantini is a recognised leader in preterm lung injury research with expertise in the preterm lamb model, mass-spectrometry-based proteomics and pulmonary morphology and cellular composition assessment. Over her post-doctoral career, she has published a total of 41 publications (>700 citations) including 16 first author publications and 4 last author publications. She founded the Neonatal Proteomics program at MCRI to provide comprehensive analysis of the molecular events underlying preterm lung injury in the sheep model and has since translated this success to the clinic, leading the first study of the preterm plasma proteome.
Dr. Pereira-Fantini is a scientist and Leader of the Molecular Lung Injury program of the Neonatal Research group (Murdoch Children’s Research Institute). Since obtaining her PhD from The University of Melbourne (2005), her career has focused on...
Dr. Pereira-Fantini is a scientist and Leader of the Molecular Lung Injury program of the Neonatal Research group (Murdoch Children’s Research Institute). Since obtaining her PhD from The University of Melbourne (2005), her career has focused on using preclinical animal models to define the injury mechanisms underlying paediatric disease. Her research focuses on using innovative methods to (1) define the cellular events underlying preterm lung injury initiation, (2) identify new treatment targets and (3) develop tests for the early detection of lung injury.

Dr Pereira-Fantini is a recognised leader in preterm lung injury research with expertise in the preterm lamb model, mass-spectrometry-based proteomics and pulmonary morphology and cellular composition assessment. Over her post-doctoral career, she has published a total of 41 publications (>700 citations) including 16 first author publications and 4 last author publications. She founded the Neonatal Proteomics program at MCRI to provide comprehensive analysis of the molecular events underlying preterm lung injury in the sheep model and has since translated this success to the clinic, leading the first study of the preterm plasma proteome.

Top Publications

  • Oakley, RB, Tingay, DG, McCall, KE, Perkins, EJ, Sourial, M, Dargaville, PA, Pereira-Fantini, PM. Gestational Age Influences the Early Microarchitectural Changes in Response to Mechanical Ventilation in the Preterm Lamb Lung. Frontiers in Pediatrics 7: 325 2024
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  • Miedema, M, McCall, KE, Perkins, EJ, Oakley, RB, Pereira-Fantini, PM, Rajapaksa, AE, Waldmann, AD, Tingay, DG, van Kaam, AH. Lung Recruitment Strategies During High Frequency Oscillatory Ventilation in Preterm Lambs. Frontiers in Pediatrics 6: 436 2024
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  • Pereira-Fantini, PM, Byars, SG, McCall, KE, Perkins, EJ, Oakley, RB, Dellacà, RL, Dargaville, PA, Davis, PG, Ignjatovic, V, Tingay, DG. Plasma proteomics reveals gestational age-specific responses to mechanical ventilation and identifies the mechanistic pathways that initiate preterm lung injury. Scientific Reports 8(1) : 12616 2024
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  • Pereira-Fantini, PM, Byars, SG, Pitt, J, Lapthorne, S, Fouhy, F, Cotter, PD, Bines, JE. Unravelling the metabolic impact of SBS-associated microbial dysbiosis: Insights from the piglet short bowel syndrome model. Scientific Reports 7(1) : 43326 2024
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  • Pereira-Fantini, PM, Rajapaksa, AE, Oakley, R, Tingay, DG. Selection of Reference Genes for Gene Expression Studies related to lung injury in a preterm lamb model. Scientific Reports 6(1) : 26476 2024
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Career information