photo of Dr Tom Forbes

Dr Tom Forbes

Dr Tom Forbes

Details

Role Clinician-Scientist Fellow
Research area Stem Cell Medicine

Contact

Available for student supervision
Dr Tom Forbes is a Consultant Paediatric Nephrologist at The Royal Children's Hospital (RCH). He completed a Bachelor of Medicine/Surgery at Monash University in 2005.

He trained in paediatric nephrology at Birmingham Children’s Hospital and Nottingham University Hospital Queen’s Medical Centre in the UK before returning to Melbourne in 2013. He completed his paediatric nephrology training at RCH, becoming a Fellow of the Royal Australasian College of Physicians in 2015. He entered laboratory research in 2016 with Prof Melissa Little's Kidney Regeneration group. Tom's PhD examined the capabilities and limitations of kidney organoids as functional genomic disease models. In 2020 Tom was awarded a Clinician Scientist Fellowship by MCRI. His research interests include using kidney organoid models to forward the understanding and treatment of genetic kidney disease, neonatal nephrology and primary hyperoxaluria.

Tom is a co-lead for the MCRI Kidney Flagship and sits on the Steering Committee for the KidGen Renal Genetics Consortium. He works with the KidGen National Kidney Genomics Program to maximise genomic outcomes for patients with suspected kidney disease using research genomic sequencing and functional genomic models. Additionally, Tom is site PI for industry sponsored clinical trials in primary hyperoxaluria and has initiated a working group to improve kidney outcomes for hospitalised neonates. Tom is the National Nephrology Co-Lead of the Australian and New Zealand Chapter Neonatal Kidney Collaborative, a group with a mission to facilitate awareness and service development in neonatal nephrology care through education and coordination of local research contributions to international projects.
Dr Tom Forbes is a Consultant Paediatric Nephrologist at The Royal Children's Hospital (RCH). He completed a Bachelor of Medicine/Surgery at Monash University in 2005.

He trained in paediatric nephrology at Birmingham Children’s Hospital and...
Dr Tom Forbes is a Consultant Paediatric Nephrologist at The Royal Children's Hospital (RCH). He completed a Bachelor of Medicine/Surgery at Monash University in 2005.

He trained in paediatric nephrology at Birmingham Children’s Hospital and Nottingham University Hospital Queen’s Medical Centre in the UK before returning to Melbourne in 2013. He completed his paediatric nephrology training at RCH, becoming a Fellow of the Royal Australasian College of Physicians in 2015. He entered laboratory research in 2016 with Prof Melissa Little's Kidney Regeneration group. Tom's PhD examined the capabilities and limitations of kidney organoids as functional genomic disease models. In 2020 Tom was awarded a Clinician Scientist Fellowship by MCRI. His research interests include using kidney organoid models to forward the understanding and treatment of genetic kidney disease, neonatal nephrology and primary hyperoxaluria.

Tom is a co-lead for the MCRI Kidney Flagship and sits on the Steering Committee for the KidGen Renal Genetics Consortium. He works with the KidGen National Kidney Genomics Program to maximise genomic outcomes for patients with suspected kidney disease using research genomic sequencing and functional genomic models. Additionally, Tom is site PI for industry sponsored clinical trials in primary hyperoxaluria and has initiated a working group to improve kidney outcomes for hospitalised neonates. Tom is the National Nephrology Co-Lead of the Australian and New Zealand Chapter Neonatal Kidney Collaborative, a group with a mission to facilitate awareness and service development in neonatal nephrology care through education and coordination of local research contributions to international projects.

Top Publications

  • Rohner, K, Marlais, M, Ali, A, Decramer, S, Didsbury, M, Forbes, TA, Koskela, M, Kurt Şükür, ED, La Scola, C, Lopez, M, et al. Rituximab treatment in children with IgA vasculitis nephritis: a case series of an international cohort.. Arch Dis Child 109(11) : 958 -960 2024
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  • Dorison, A, Ghobrial, I, Graham, A, Peiris, T, Forbes, TA, See, M, Das, M, Saleem, MA, Quinlan, C, Lawlor, KT, et al. Kidney Organoids Generated Using an Allelic Series of NPHS2 Point Variants Reveal Distinct Intracellular Podocin Mistrafficking.. J Am Soc Nephrol 34(1) : 88 -109 2023
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  • Forbes, TA, Brown, BD, Lai, C. Therapeutic RNA interference: A novel approach to the treatment of primary hyperoxaluria.. Br J Clin Pharmacol 88(6) : 2525 -2538 2022
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  • Majmundar, AJ, Buerger, F, Forbes, TA, Klämbt, V, Schneider, R, Deutsch, K, Kitzler, TM, Howden, SE, Scurr, M, Tan, KS, et al. Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice.. Sci Adv 7(1) : 2021
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  • Phipson, B, Er, PX, Combes, AN, Forbes, TA, Howden, SE, Zappia, L, Yen, H-J, Lawlor, KT, Hale, LJ, Sun, J, et al. Evaluation of variability in human kidney organoids.. Nat Methods 16(1) : 79 -87 2019
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