Professor Angela Morgan
Associate Professor Angela Morgan is co-leader of the Hearing, Language and Literacy research group at Murdoch Childrens Research Institute. Angela is a Speech Pathologist and speech and language neuroscientist. She has been based at Murdoch Childrens since mid 2006, supported by NH&MRC research fellowship funding. Immediately prior to her Murdoch Childrens post, Angela completed post-doctoral training at the University College London Institute of Child Health. She worked in the Developmental Cognitive Neuroscience Unit.
Part of Angela's remit at UCL was to work on the behavioural and neural phenotype of the KE family; a three generational British family with speech disorder associated with the discovery of FOXP2. Her research experiences at UCL paved the way for her current cross-disciplinary collaborations with cognitive neuroscientists, neurologists, neuropsychologists, clinical and molecular geneticists and neuroimaging experts.
Angela's research is published in well-respected cross-disciplinary journals including Brain, Neurology, Cortex and Neuroscience and Biobehavioural Reviews. She also publishes in discipline specific journals to ensure her translational clinical work reaches the appropriate audience. Angela receives regular international keynote speaker invitations in countries such as the USA and Germany. She is an Editorial Board member for a number of international journals including Developmental Cognitive Neuroscience; Child: Care, Health and Development and BMC Pediatrics.
Her work is supported by competitive funding bodies including the Australian Research Council and NH&MRC. She is a CI on two NH&MRC Centre of Research Excellence grants in (i) Childhood Language and (ii) Psychosocial rehabilitation after traumatic brain injury, and leads the neurobiological streams of these programs.
- 2015, German Humboldt Foundation Experienced Research Fellowship
- 2013, Murdoch Childrens Research Early to Mid Career Researcher Award
- 2013, Australian Academy of Science Theo Murphy Travel Award
- 2012, Elizabeth Usher Speech Pathology Australia Award and Keynote presentation (peer recognition of original research contribution to the field)
- 2010, Victorian Young Tall Poppy Award, Australian Institute of Policy and Science, (awarded to 9 early career scientists in Victoria for early career research success)
- 2010, National Health and Medical Research Council Achievement Award
- 2009, National Health and Medical Research Council Career Development Award
- 2008, Australian Academy of Science Theo Murphy Travel Award
- 2008, Harold Mitchell International Travelling Fellowship
*Significant career breaks 2010, 2013
Angela's research program examines the neurobiological bases of childhood communication disorders. This involves two streams. First, Angela's team uses structural and functional imaging techniques to explore neural markers for outcome associated with inherited or acquired childhood speech and language disorders.
A key collaborator on this work is Dr. Frederique Liegeois at the University College London Institute for Child Health. Secondly, her team conduct sophisticated speech and language phenotyping to (i) elucidate genotype-phenotype relationships or (ii) inform molecular genetic analysis to identify novel single genes associated with dominant speech and language disorders.
This work is undertaken in collaboration with leading Australian and international scientists. Collaborators include Prof. Ingrid Scheffer (child neurologist) and Dr. Michael Hildebrand (molecular geneticist) at the University of Melbourne; A/Prof. David Amor (clinical geneticist at the Victorian Clinical Genetics Service), Prof. Simon Fisher (biologist) of the Max Planck Institute for Psycholinguistics, Nijmegen, co-founder of FOXP2; Dr. David Koolen (clinical geneticist), Radboud Medical Centre, Nijmegen, co-founder of Koolen de Vries Syndrome; and Prof. Nancy Kanwisher and Dr. Evelina Federenko (cognitive neuroscient) at Harvard and MIT Boston.
- Understanding the brain basis of language development
- Elucidating the neural pathways and genetic basis of speech
Reilly S, McKean C, Morgan A, Wake M. (2015) Common Developmental Language and Speech Impairments. BMJ (Clinical Review); 350:h2318.
Turner SJ, Mayes AK, Verhoeven A, Mandelstam SA, Scheffer IE, Morgan AT.* (2015). GRIN2A: An aptly named gene for speech dysfunction. Neurology, 84(6):586-93. *Joint senior author.
Morgan AT, Mei C, Da Costa A, Fifer J, Lederer D, Benoit V, McMillin M, Buckingham KJ, Bamshad MJ, Pope K, White SM. (2015) Speech and language in a genotyped cohort of individuals with Kabuki syndrome. American Journal of Medical Genetics Part A. [Epub ahead of print].
Lum JA, Conti-Ramsden G, Morgan AT, Ullman MT. (2014). Procedural learning deficits in specific language impairment (SLI): A meta-analysis of serial reaction time task performance Cortex, E-pub Nov 8.
Morgan AT*, Eadie P*, Ukoumunne OC, Ttofari-Eecen K, Wake M, Reilly S. (2015). Speech Disorder at 4 years: Prevalence, Co-Morbidities, and Predictors in a community cohort of children. Developmental Medicine and Child Neurology, 57(6):578-84 *Joint first author.
Liégeois FJ, Mahony K, Connelly A, Pigdon L, Tournier JD, Morgan AT. (2013). Pediatric traumatic brain injury: Language outcomes and their relationship to the arcuate fasciculus. Brain and Language, 127(3):388-98.
Turner S, Hildebrand M, Block S, Damiano J, Fahey M, Reilly S, Bahlo M, Scheffer I, Morgan A. (2013). Small intragenic deletion of FOXP2 associated with childhood apraxia of speech and dysarthria. American Journal of Medical Genetics Part A, 161(9):2321-6.
Morgan AT, Masterton R, Pigdon L, Connelly A, Liegeois F. (2013). FMRI of chronic dysarthric speech after childhood brain injury: limited efficiency of a compensatory network. Brain, 136(Pt2):646-57.
Liegeois F, Tournier J-D, Pigdon L, Connelly A, Morgan AT. (2013). Corticobulbar tract changes as predictors for dysarthria in childhood ?brain injury. Neurology, 80(10):926-32.
Liégeois FJ, Morgan AT. (2012). Neural bases of childhood speech disorders: lateralization and plasticity for speech functions during development. Neuroscience and Biobehavioural Reviews, 36(1):439-458.
- Australian Research Council
- NHMRC Centre of Research Excellence (in Child Language)
- NHMRC Centre of Research Excellence (in Traumatic Brain Injury)
- The Waterloo Foundation
- Simons Variation in Individuals Project (United States)
- Humboldt Foundation (Germany)