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A/Professor Margie Danchin
A/Prof Margie is consultant paediatrician within the Department of Paediatrics, University of Melbourne and Murdoch Childrens Research Institute (MCRI). She is Group Leader, Vaccine acceptance, Uptake and Policy, at MCRI, and is an immunisation expert with over ten years of experience in vaccine research and clinical work, both in Australia and in resource poor settings. She has expertise in vaccine clinical trials, vaccine safety, program evaluation, health system strengthening and implementation research in low resource settings, social science and vaccine policy. Her research program is focused on improving vaccine confidence, demand and uptake of licensed vaccines in different settings and populations.
This is achieved by developing, trialing and translating effective, multi-component interventions in pregnancy and early childhood, in at risk populations and in low resource settings. She is also developing a new tool to enable diagnosis of the causes of under-vaccination in different populations to ensure cost-effective, targeted interventions to improve vaccine uptake in children under 5 years. She is at the forefront of understanding vaccine confidence nationally and internationally and has strong collaborations with leaders in the field.
She is the current chair of the Collaboration on Social Science in Immunisation (COSSI) Group, an initiative of the National Centre for Immunisation Research and Surveillance (NCIRS), a member of Sabin's Vaccine and Acceptance Research Network (VARN) steering group and is engaged as a WHO consultant to address the rise in measles cases and vaccine confidence issues in the Philippines.
Consultant Paediatrician, General Medicine and Immunisation Service, Royal Children's Hospital, Melbourne
Associate Professor and David Bickart Clinician Research Fellow, Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, and honorary Senior Research Fellow School of Population Health
Research Fellow, Murdoch Children's Research Institute
Honorary Senior Research Fellow, Telethon Kids Institute
2019: University of Sydney Vice-Chancellor's Awards for Excellence in the category of “Outstanding Research Engagement and Innovation" for Sharing Knowledge About Immunisation, Team Award
2018: Department of Paediatrics award for academic excellence for an MCR, University of Melbourne
2018-20: David Bickart Clinician Research Fellowship, University of Melbourne
2011: Prize for most cited Australian Paediatric Surveillance Unit (APSU) Surveillance Paper – Intussusception
1. To improve vaccine confidence and uptake of licensed vaccines in different settings and populations by developing, trialling and translating effective, multi-component interventions:
(i) in pregnancy and early childhood to improve vaccine acceptance and uptake of maternal and childhood vaccines
(ii) in at risk populations, such as children with a developmental disability (< 5yo and 11-13yo), high risk medical conditions (flu vaccine), refugee and asylum seekers
(iii) in low resource settings, such as clinic led interventions to strengthen service delivery and vaccine uptake at the clinic level
2. To develop a validated tool to monitor rates of vaccine hesitancy in children under five by building a comprehensive tool (VBAT) that incorporates the underlying drivers of vaccine acceptance and access and validating the refined tool against vaccine uptake
The aim is to use VBAT:
(i) for population-level opinion surveillance
(ii) for evaluation and quality improvement of immunisation programs at a state and/or regional level
(iii) for use by local program delivery teams
(iv) by clinicians with individual parents to improve vaccination uptake.
3. To develop an evidence base for the implementation of immunisation legislation relating to exemptions to generate evidence to support vaccine policy in Australia
- P3-MumBubVax: a novel, milti-component antenatal intervention to increase maternal and childhood vaccination coverage (P3+) at the Practice, Provider and Parent levels.
- Immunisation of young people with disabilities in specialist school settings in Victoria, Australia.
- Khusela Immunisation Study: strengthening clinic level immunisation service delivery in Western Cape Province, South Africa: WHO funded project.
- Vaccine barriers Assessment Tool.
- Optimising influenza vaccine uptake in high risk children: a mixed methods stud.
- ORVAC – Optimising Rotavirus Vaccine in Aboriginal Children.
- Characterising clinical presentation and outcomes of children presenting with seizures following vaccination
- Ms Jenny O'Neill, Dr Margie Danchin Dr Giuliana Antolovich, Dr Sally Lima, Prof Fiona Newall. Adolescent immunisation in young people with disabilities in Australia. Med J Aust.
- Kaufman J, Attwell K, Hauck Y, Omer SB, Danchin M. Vaccine discussions in pregnancy: interviews with midwives to inform design of an intervention to promote uptake of maternal and childhood vaccines. Hum Vaccin Immunother. 2019:1-10.
- Norman DA, Danchin M, Van Buynder P, Moore HC, Blyth CC, Seale H. Caregiver's attitudes, beliefs, and experiences for influenza vaccination in Australian children with medical comorbidities. Vaccine. 2019;37(16):2244-8.
- Catalano C, Cranswick NE, Robinson J, Grindlay J, Creati M, Danchin MH, et al. Unintended consequences of a cautious approach to e-cigarette laws. Med J Aust. 2019;210(3):143- e1.
- O'Neill J, Newall F, Antolovich G, Lima S, Danchin M. The uptake of adolescent vaccinations through the School Immunisation Program in specialist schools in Victoria, Australia. Vaccine. 2019;37(2):272-9.
- Danchin M, Gulenc A, Efron D, Sciberras E, Symeonides C, Hiscock H. Trends in Prevalence and Management of Childhood Anxiety by Australian Pediatricians. Acad Pediatr. 2019;19(1):35-43.
- Danchin MH, Costa-Pinto J, Attwell K, Willaby H, Wiley K, Hoq M, Leask, J, Perrett, K. P, O'Keefe, J, Giles, M. L, Marshall, H. Vaccine decision-making begins in pregnancy: Correlation between vaccine concerns, intentions and maternal vaccination with subsequent childhood vaccine uptake. Vaccine. 2018;36(44):6473-9.
- Paxton GA, Spink PCG, Danchin MH, Tyrrell L, Taylor CL, Casey S, et al. Catching up with catch-up: a policy analysis of immunisation for refugees and asylum seekers in Victoria. Aust J Prim Health. 2018.
- Crawford NW, McMinn A, Royle J, Lazzaro T, Danchin M, Perrett KP, et al. Recurrence risk of a hypotonic hyporesponsive episode in two Australian specialist immunisation clinics. Vaccine. 2018;36(41):6152-7.
- O'Grady KF, Chang AB, Cripps A, Mulholland EK, Smith-Vaughan H, Wood N, et al. The clinical, immunological and microbiological impact of the 10-valent pneumococcal-Protein D conjugate vaccine in children with recurrent protracted bacterial bronchitis, chronic suppurative lung disease and bronchiectasis: A multi-centre, double-blind, randomised controlled trial. Hum Vaccin Immunother. 2018:1-12