Professor Anne-Louise Ponsonby
As an epidemiologist and public health physician, Professor Anne-Louise Ponsonby is interested in the broader aspects of public health and preventative medicine. Her work aims to provide new knowledge to assist public health guidelines and policy to achieve reduction in disease burden at the population level.
She is also involved with Multiple Sclerosis Australia as an ongoing consultant with regard to health education and promotion activities; a national media spokesperson.
Professor Ponsonby studies how early environment can influence the risk of an individual attaining a range of immune and other disorders including multiple sclerosis, type 1 diabetes, food allergy and asthma. Her work involves undertaking a life course perspective on how various environmental and lifestyle factors operate to precipitate these immune disorders. Environmental factors operate on genetically susceptible individuals, thus genetics is taken into consideration also.
Professor Ponsonby is also interested in gene environment interactions and the genetic determinants of these disorders. Her work is collaborative and involves working with many groups internationally, nationally and locally. She is on the Editorial Board of the journal Multiple Sclerosis.
- Barwon Infant Study
- The AusImmune Study
- The Paediatric Autoimmune Disease Consortium
- The International Child Cancer Cohort Consortium
- The PrevAnz Trial. This is a large randomised controlled trial that is investigating whether various doses of vitamin D supplementation can slow the progression to multiple sclerosis amongst those presenting with a first clinical demyelinating event in Australia and New Zealand.
Higher 25-hydroxyvitamin D Is Associated with Lower Relapse Risk in Multiple Sclerosis; Simpson, Jr.; Taylor, B; Blizzard, L, Ponsonby A-L et al. Annals of Neurology 2010: 68; 193-203
Staples J, Ponsonby A-L, Lim L. Prenatal ultraviolet radiation exposure, month of birth and subsequent risk of multiple sclerosis: a longitudinal analysis. BMJ 2010;340:c1640.
Sun exposure and vitamin D are independent risk factors for CNS demyelination Lucas, R. M.; Ponsonby, A. -L.; Dear, K.; et al. Neurology 2011 76: 540-548 .
Dwyer T, Ponsonby A-L, Ukoumunne OC, Pezic A, Venn A, Shaw J, Dunstan D, Barr E, Blair SN, Cochrane J, Zimmet P. Association between change in daily steps over five years and subsequent adiposity and insulin sensitivity in the AusDiab cohort. BMJ. 2011 Jan 13;342:c7249.
Ponsonby AL, Lucas RM, van der Mei IA, Dear K et al. Offspring number, pregnancy, and risk of a first clinical demyelinating event: the AusImmune Study. Neurology. 2012 Mar 20;78(12):867-74.