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Professor Stephen Graham
Professor Steve Graham is Leader of International Child Health Group at the Murdoch Childrens Research Institute.
Prof Graham is a Paediatrician with 20 years' experience in international child health including African and Asia-Pacific regions. He has worked in Papua New Guinea (1985), Thailand (1993/4) and Malawi (1995-2007). While with the College of Medicine in Malawi, he helped establish the Malawi-Liverpool-Wellcome Trust clinical research programme in Blantyre and was Deputy Director from 2001 to 2007.
Prof Graham was awarded Leverhulme Medal for distinguished contribution to tropical medicine by Liverpool School of Tropical Medicine, United Kingdom, in 2007. He was appointed to current post at University of Melbourne in 2008. Steve has since developed collaborative links in Asia-Pacific region and works part-time for the International Union Against Tuberculosis and Lung Disease.
He is a founding member and current chair of the Child Tuberculosis (TB) subgroup of World Health Organization (WHO) Stop TB Partnership, as well as being a member of the Strategic Technical Advisory Group on TB for the WHO, as well as research committees for Wellcome Trust, UK, and National Institutes of Health, USA.
- Professor of international Child Health, the University of Melbourne
- Leverhulme Medal for distinguished contribution to tropical medicine, 2007
Particular interests of Professor Graham include pneumonia and TB as well as invasive bacterial disease, especially invasive salmonellosis in tropical Africa and neonatal sepsis. His PhD was awarded from the University of Amsterdam on "Impact of HIV on respiratory disease in Malawian children".
He works closely with WHO and national disease control programmes helping develop management guidelines and undertake operational research, with the aim of seeking to improve implementation of TB management for children and adolescents. He has published over 150 peer reviewed publications on a wide range of child health challenges in resource-limited settings
- Evaluation and implementation of community-based child TB contact screening and management.
- Improving neonatal care in Viet Nam and reducing the burden of neonatal sepsis.
- Improving the care of children with malnutrition and pneumonia.
- Improving diagnostics and care for the sick, febrile African child.
- Improving diagnosis and management of TB in children and adolescents.
Graham SM, Cuevas LE, Jean-Philippe P, et al. Clinical case definitions for classification of intrathoracic tuberculosis in children: an update. Clin Infect Dis 2015; 61(suppl 3):S179-S187
Chisti M, Salam MA, Smith JH, Ahmed T, Pietroni MAC, Shahunja KM, Shahid ASMSB, Faruque ASG, Ashraf H, Bardhan PK, Uzzaman S, Graham SM, Duke T. Bubble continuous positive airway pressure for children with severe pneumonia and hypoxaemia in Bangladesh: an open randomised controlled trial. Lancet 2015; 386: 1057-1065
Oliwa JN, Karumbi JM, Marais BJ, Madhi SA, Graham SM. Tuberculosis as a cause or comorbidity of childhood pneumonia in tuberculosis endemic settings: a systematic review. Lancet Resp Med 2015; 3: 235-243
Triasih R, Duke T, Robertson C, Graham SM. A prospective evaluation of the symptom-based screening approach to the management of children that are contacts of tuberculosis cases. Clin Infect Dis 2015; 60: 12-18
Graham SM, Sismanidis C, Menzies HJ, Detjen AK, Marais BJ, Black RE. Importance of tuberculosis control to address child survival. Lancet 2014; 383: 1605-1607
Graham SM, Donald PR. Death and disability: the outcomes of tuberculous meningitis. Lancet Infect Dis 2014; 14: 902-904
Graham SM. Molecular diagnosis of child pneumonia: high yield, uncertain specificity. Clin Infect Dis 2014; 59: 686-687
Graham SM, Triasih R. More evidence to support screening of child contacts of tuberculosis cases: if not now, then when? Clin Infect Dis 2013: 57: 1693-1694
Crawford NW, Graham SM. EV71 vaccine: protection from a previously neglected disease. Lancet 2013; 381: 1968-1970
Graham SM, Ahmed T, Amanullah F, et al. Evaluation of TB diagnostics in children: 1. Proposed clinical case definitions for classification of intra-thoracic tuberculosis disease. Consensus from an Expert Panel. J Infect Dis 2012; 205 (suppl 2): S199-208
- IIE Research Investment Funding, MCRI, 2014. A study of pneumonia in Indonesian children and association with vitamin D status.
- TB CRE seed funding grant, 2013. A situational analysis of the global burden of TB and TB/HIV in adolescents.
- TB Care I, USAID, 2013. Childhood TB on-line training for NTP, district and community health workers.
- TB Care I, USAID, 2013.Development of child TB and MDR-TB guidelines for Somalia.
- National Health and Medical Research Council, 2012. Centre of Research Excellence on Tuberculosis Control: from discovery to public practice and policy. CRE Grant 1043225.