Core facilities
Murdoch Children's Stem Cell Medicine is internationally recognised for its research using human induced pluripotent stem cells (iPSC) and their subsequent differentiation into specialised human cell types and multicellular human 3D organoids. To support this research, MCRI has established state-of-the-art facilities. All facility services are available to internal and external researchers across the world.
iPSC Derivation and Gene Editing Facility
Through the support from the Stafford Fox Medical Research Fund, the Murdoch Children's Research Institute established it’s induced pluripotent stem cell (iPSC) Derivation and Gene Editing Facility. This has accelerated MCRI stem cell research by facilitating the derivation and distribution of induced pluripotent stem cell lines, including lines derived from patient cells. The Facility has gene editing capacity, to meet growing demand for gene corrected, targeted mutation and reporter lines.
Stem Cell Disease Modelling & Drug Screening Facility
The Stafford Fox Disease Modelling Facility at MCRI offers an automated platform for high throughput/high content drug screening of patient’s induced pluripotent stem cell (iPSC) derived tissues. The facility was design to enable researchers with automated data acquisition tools and data processing for modelling disease and help achieve a better understanding of the underlying molecular mechanism.