International Childhood Cancer Cohort Consortium (I4C)

Murdoch Childrens Research Institute is playing a key role in the world's largest study into childhood cancer.

Finding Causes of Childhood Cancer

This innovative study possibly provides the greatest opportunity for finding a preventable cause of childhood cancer. It aims to examine associations between environmental exposures and the incidence of childhood cancers by pooling prospective population data from one million pregnant mothers and their babies.

International Collaboration

Around the world, several large infant/child prospective studies have been launched to examine environmental and biological determinants of common diseases. The rarity of virtually all forms of childhood cancer, however, prevent even large cohort studies from examining the possible relationship of common exposures with common types of childhood cancer due to inadequate sample size.

Murdoch Childrens' Role

Murdoch Childrens has had a major role in the study concept and planning and is functioning as the I4C International Data Coordinating Centre. Data is being pooled and analysed to examine environmental and genetic factors that differ between those children who get cancer and those who don't.

The International Data Coordinating Centre is under the direction of Professor Terry Dwyer and includes Dr Gabriella Tikellis as Project Manager and Mr Luke Stevens as Data Management Coordinator.

The I4C Team associated with the Murdoch Childrens:

Principle Investigator (now based at The George Institute for Global Health, UK)
Terry Dwyer
E: [email protected]

Project Manager
Gabriella Tikellis
E: [email protected]

Lead Epidemiologist
Anne-Louise Ponsonby
[email protected]

Data Management Coordinator
Luke Stevens
[email protected]

Epigenetic Consultant
Richard Saffery
E [email protected]

Statistical Support

Statistical Advisor
Stan Lemeshow
E [email protected]

Senior Biostatistician
Gary Phillips
E [email protected]

 

Further Information

Further information can be obtained by contacting Terry Dwyer, Gabriella Tikellis or the nominated heads of the Working Groups.

NCI I4C Portal

https://communities.nci.nih.gov/i4c

The National Children's Study

The National Children's Study I4C Site

Acknowledgements

The I4C wish to acknowledge the following funding partners: