Pneumococcal vaccine study in infants

Research area: Infection and Immunity | Status: Active

young adult

The Vaccine & Immunisation Research Group of the Murdoch Children’s Research Institute is conducting a research study on an investigational vaccine against pneumococcal infections in infants.

Pneumococcal disease is caused by a type of bacterium called Streptococcus pneumoniae. This bacterium is a major cause of infection that may be in the ears, sinuses, blood, lungs or brain.

Pneumococcal disease is caused by a type of bacterium called Streptococcus pneumoniae. This bacterium is a major cause of infection that may be in the ears, sinuses, blood, lungs or brain.

Overview

Pneumococcal disease is caused by a type of bacterium called Streptococcus pneumoniae. This bacterium is a major cause of infection that may be in the ears, sinuses, blood, lungs, or brain. 

There is already a licensed vaccine which protects against pneumococcal disease and this is being used to compare to the study vaccine.

This study compares the study vaccine with a currently licensed vaccine to study its safety, how well it is tolerated, and how well your child responds to the investigational vaccine.

Information for participants

We are looking for healthy adolescents and young adults aged between 10 and 17 years inclusive, to participate in a study looking at an investigational whooping cough (pertussis) vaccine.

Whooping cough disease is caused by bacteria called Bordetella pertussis. Whooping cough is a severe respiratory tract infection that kills almost 200,000 children every year worldwide. 

The number of infections is increasing around the world, especially in adolescents and adults, and this is thought to be because of waning immunity from the currently recommended pertussis vaccines.

You may be eligible to participate if you:

  • Are aged between 10 and 17 years (inclusive)
  • Are in generally good health, and
  • Have received two or more acellular pertussis vaccines in the past

Participants in the study will be required to attend up to 4 visits and respond to up to one follow-up phone call over a 16-week period (home visits may be possible). We will reimburse participants for travel/time costs incurred.

The Sydney Children’s Hospitals Network (SCHN) Human Research Ethics Committee (HREC) has approved this study (approval number: 2020/ETH02847). 

If you have any concerns or complaints about any aspect of the project or the way it is being conducted, you may contact the Executive Officer of the SCHN HREC on (02) 9845 1253 or [email protected] 

Contact us

Pneumococcal Vaccine Study
Murdoch Children's Research Institute
The Royal Children's Hospital
50 Flemington Road
Parkville VIC 3052
Australia

Ph: +61 3 8344 9325
Email: [email protected]

 
  
child in hospital

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