Dr Jana Hagen
Dr Jana Hagen
Dr Jana Hagen is a Senior Research Officer in the Blood Development laboratory at Murdoch Children’s Research Institute (MCRI). A major focus of her work is to generate transplantable hematopoietic stem cells (HSCs) from human pluripotent stem cells for tissue repair and regeneration, disease modeling and the testing of pharmaceuticals and other therapeutic products. This work is supported by grants from the NHMRC and the Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW.
Dr Jana Hagen is a Senior Research Officer in the Blood Development laboratory at Murdoch Children’s Research Institute (MCRI). A major focus of her work is to generate transplantable hematopoietic stem cells (HSCs) from human pluripotent stem...
Dr Jana Hagen is a Senior Research Officer in the Blood Development laboratory at Murdoch Children’s Research Institute (MCRI). A major focus of her work is to generate transplantable hematopoietic stem cells (HSCs) from human pluripotent stem cells for tissue repair and regeneration, disease modeling and the testing of pharmaceuticals and other therapeutic products. This work is supported by grants from the NHMRC and the Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW.
Top Publications
- Hagen, J, Sarkies, P, Selkirk, ME. Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis.. PLoS Pathog 17(1) : e1009286 2021 view publication
- Hagen, J, Scheerlinck, J-PY, Gasser, RB. Knocking down schistosomes - promise for lentiviral transduction in parasites.. Trends Parasitol 31(7) : 324 -332 2015 view publication
- Hagen, J, Young, ND, Every, AL, Pagel, CN, Schnoeller, C, Scheerlinck, J-PY, Gasser, RB, Kalinna, BH. Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo.. Nat Commun 5: 5375 2014 view publication
- Hagen, J, Ghosh, S, Sarkies, P, Selkirk, ME. Gene editing in the nematode parasite Nippostrongylus brasiliensis using extracellular vesicles to deliver active Cas9/guide RNA complexes. Frontiers in Parasitology 2: 1071738 -1071738 2023 view publication
- de Lange, A, Prodjinotho, UF, Tomes, H, Hagen, J, Jacobs, B-A, Smith, K, Horsnell, W, Sikasunge, C, Hockman, D, Selkirk, ME, et al. Taenia larvae possess distinct acetylcholinesterase profiles with implications for host cholinergic signalling.. PLoS Negl Trop Dis 14(12) : e0008966 2020 view publication
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