photo of Dr Jana Hagen

Dr Jana Hagen

Dr Jana Hagen

Details

Role Senior Research Officer
Research area Stem cell biology
Dr Jana Hagen is a Senior Research Officer in the Blood Development laboratory at the Murdoch Children’s Research Institute. A major focus of her work is to generate transplantable hematopoietic stem cells (HSCs) from human pluripotent stem cells for tissue repair and regeneration, disease modeling and the testing of pharmaceuticals and other therapeutic products. This work is supported by grants from the NHMRC and the Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW.
Dr Jana Hagen is a Senior Research Officer in the Blood Development laboratory at the Murdoch Children’s Research Institute. A major focus of her work is to generate transplantable hematopoietic stem cells (HSCs) from human pluripotent stem cells...
Dr Jana Hagen is a Senior Research Officer in the Blood Development laboratory at the Murdoch Children’s Research Institute. A major focus of her work is to generate transplantable hematopoietic stem cells (HSCs) from human pluripotent stem cells for tissue repair and regeneration, disease modeling and the testing of pharmaceuticals and other therapeutic products. This work is supported by grants from the NHMRC and the Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW.

Top Publications

  • Hagen, J, Young, ND, Every, AL, Pagel, CN, Schnoeller, C, Scheerlinck, J-PY, Gasser, RB, Kalinna, BH. Omega-1 knockdown in Schistosoma mansoni eggs by lentivirus transduction reduces granuloma size in vivo. Nature Communications 5(1) : 5375 2023
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  • Hagen, J, Sarkies, P, Selkirk, ME. Lentiviral transduction facilitates RNA interference in the nematode parasite Nippostrongylus brasiliensis. PLOS Pathogens 17(1) : e1009286 2023
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  • Hagen, J, Scheerlinck, J-PY, Gasser, RB. Knocking down schistosomes – promise for lentiviral transduction in parasites. Trends in Parasitology 31(7) : 324 -332 2015
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  • Hagen, J, Ghosh, S, Sarkies, P, Selkirk, ME. Gene editing in the nematode parasite Nippostrongylus brasiliensis using extracellular vesicles to deliver active Cas9/guide RNA complexes. Frontiers in Parasitology 2: 1071738 2023
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  • Vaux, R, Schnoeller, C, Berkachy, R, Roberts, LB, Hagen, J, Gounaris, K, Selkirk, ME. Modulation of the Immune Response by Nematode Secreted Acetylcholinesterase Revealed by Heterologous Expression in Trypanosoma musculi. PLOS Pathogens 12(11) : e1005998 2023
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