Professor Mimi Tang
Professor Mimi Tang has an international and national profile in the field of allergic and immune deficiency disorders, and has shown strong intellectual leadership and contribution to this field of research. Evidence of this leadership is shown by her participation on relevant international and national expert and peer review committees, as well as contributions to health policy.
Professor Tang is an expert consultant to the Victorian Department of Education and Early Childhood Development, on issues related to anaphylaxis management policy in school and day care settings. She also works with Australasian Society of Clinical Immunology and Allergy (ASCIA to develop resources to support health professionals in anaphylaxis management as well as educational resources for people diagnosed with or at risk of anaphylaxis and their families or carers.
Professor Tang has more than 20 years' experience in the investigation of basic immunological mechanisms underlying allergic disease pathogenesis, and correlation of mechanistic studies with clinical outcomes. She has worked in the field of probiotics, prebiotics and gut microbiota for the past 10 years and has expertise in the investigation of gut microbiota changes in allergic disease. She is also a leader in the field of primary immune deficiency in the Asia Pacific region.
Over the course of her career, Professor Tang has been awarded research grants with a total in excess of $20.5 million and has authored over 190 peer reviewed journal articles, invited reviews, and book chapters.
Professor Tang has demonstrated an ongoing and continued involvement in teaching both undergraduate and postgraduate University of Melbourne students, as well as the supervision of advanced trainees in specialist Immunology Allergy physician training
- 1995: International Fellowship Award, Pharmacia
- 1995: Research Fellowship Award, Allen and Hanbury's Research Institute ** First time awarded to a Non-US Citizen
- 1996: Presidents Grant-in-Aid Award, American Academy of Allergy Asthma and Immunology ** First time awarded to a Non-US Citizen
- 2009: Most Appropriate Care Award, Victorian Public Healthcare, Department of Health
- 1998: Clinical Investigator Award, Australian Society of Clinical Immunology Allergy
- 1994: Fulbright Fellowship (deferred), Australian-American Fulbright Commission
- 1991 - 1994: Postgraduate Research Scholarship, National Health & Medical Research Council
- 1993: JJ Billings Fellowship, Royal Australasian College of Physicians
- Nestle Travel Scholarship, Australian College of Paediatrics 1993
- 1992: Young Investigator Award, Australian Society of Clinical Immunology Allergy
Professor Tang's research investigates the relationship between intestinal microbiota and early life immune programming, and their roles in modulating the development of allergic disease. Novel approaches to treatment and prevention of allergic disease are also evaluated in randomised controlled clinical trials.
- PPOIT study - Probiotic and Peanut Oral Immunotherapy for treatment of peanut allergy. This project evaluates a novel approach to treatment of peanut allergy, with the aim of inducing long –lasting tolerance to peanut. Immune mechanisms of tolerance are also investigated. Recruitment for this study has closed but participants are still active in a follow up study.
- RELAX study – A collaborative study with The Royal Children's Hospital, Brisbane and the Princess Margaret Hospital for Children, Perth. This study examines whether a winter only treatment with Omalizumab (Xolair) will reduce asthma exacerbations in children aged 6 to 15 years. For more information contact study coordinator on 83416229.
- OM-85 study – A collaborative study with the Royal Children's Hospital, Brisbane. This study investigates whether a winter only treatment with Om-85 will reduce lower respiratory infections in atopic children with asthma aged 6 to 12 years. For more information contact study coordinator on 83416229.
- ProVac study – A pilot study looking at the benefits of a probiotic Bio-7 to improve protection against pneumococcal disease in early life when given in conjunction with the Pneumococcal vaccine. This study has finished recruiting but participants are still active on the study.
- ProPrems Allergy – this is a sub-study within a multicentre trial evaluating probiotic supplementation for the prevention of sepsis in low birth weight very premature infants. This sub-study will investigate the effect of probiotics on prevention of allergic disease in premature infants and the immune mechanisms associated with development of allergic disease. This study has finished recruiting but participants are still active on the study.
Tang MLK, Allen KJ. “Kids Food Allergies for Dummies". Wiley Publishing, Australia 2012
Ismail I H, Licciardi P V, Oppedisano F, Boyle R.J, Tang MLK. Relationship between breast milk sCD14, TGF-ß1 and total IgA in the first month and development of eczema during infancy. Pediatr Allergy Immunol 2013;24(4):352-60
A Balloch, PV Licciardi, MLK Tang. Serotype-specific anti-pneumococcal IgG and immune competence: critical differences in interpretation criteria when different methods are used. Journal of Clinical Immunology 2013;33:335-341
GD Pinczower, NA Bertalli, N Bussmann, Melisa Hamidon, KJ Allen, A DunnGalvin, J O'B Hourihane, LC Gurrin, MLK Tang. The effect of provision of an adrenaline auto-injector on quality of life in children with food allergy. J Allergy Clin Immunol 2013;131(1):238-40 e1
SG Royce, C Lim, RC Muljadi, CS Samuel, K Ververis, TC Karagiannis, AS Giraud, and MLK Tang. Trefoil factor 2 reverses airway remodeling changes in allergic airways disease. Am J Respir Cell Mol Biol 2013;48(1):135-44
IH Ismail, F Oppedisano, SJ Joseph, RJ Boyle, PV Licciardi, RM Robins-Brown, MLK Tang. Reduced gut microbial diversity in early life is associated with later development of eczema but not atopy in high risk infants. Pediatric Allergy and Immunology 2012;23:674-81
AW Burks, MLK Tang, S Sicherer, A Muraro, P Eigenman, M Ebisawa, A Fiochi, W Chiang, K Beyer, R Wood, J Hourihane, SM Jones, G Lack, HA Sampson. ICON:Food Allergy. J Allergy Clin Immunol 2012;129:906-920
PV Licciardi, A Balloch, FM Russell, RL Burton, J Lin, MH Nahm, EK Mulholland MLK Tang. Pneumococcal polysaccharide vaccine at 12 months of age produces functional immune responses. J Allergy Clin Immunol. 2012;129:794-800
RJ Boyle, IH Ismail, S Kivivuori, PV Licciardi, RM Robins-Browne, L-J Mah, C Axelrad, S Moore, S Donath, JB Carlin, SJ Lahtinen, MLK Tang. Lactobacillus GG treatment during pregnancy for the prevention of eczema: a randomised controlled trial. Allergy 2011;66:509-516
WK Liew, E Williamson, MLK Tang. Anaphylaxis fatalities and admissions in Australia. J Allergy Clin Immunol 2009;123:434-442
- National Health and Medical Research Council
- Murdoch Childrens Research Institute