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Dr Ken Pang
Ken Pang is a paediatrician at the Royal Children’s Hospital, where he works to help support transgender young people and their families. He is also an Associate Professor (Honorary) at the University of Melbourne and leads a research team at the Murdoch Children’s Research Institute whose aim is to improve the clinical management of transgender children and adolescents. Across his research career, Ken’s interests have spanned genetics, immunology and most recently transgender health, and his research has been recognised via receipt of multiple awards/fellowships. Ken’s >70 papers have featured in journals such as Science, Immunity, and the BMJ and been cited >12,000 times.
Melbourne Children’s Clinician Scientist Fellowship, 2016-21.
Career Development Fellowship, Royal Australasian College of Physicians, 2019
CJ Martin Overseas Biomedical Fellowship, National Health & Medical Research Council, 2008-10, 2013-14
Sir Keith Murdoch Fellowship, American Australian Association, 2011
Fulbright Postdoctoral Scholarship, Australian - American Fulbright Commission, 2008
Dean's Award for Excellence in a PhD Thesis, University of Melbourne, 2008
Victorian Premier's Commendation for Medical Research, 2006
Ken’s current research focuses on transgender health, and is described in more detail here.
As a continuation of his previous lab-based research, Ken is also actively working to improve the understanding and treatment of a rare genetic skin disorder, known as Epidermolysis Bullosa (EB). This work is currently being supported by DEBRA Australia, the Australasian College of Dermatologists and the EB Research Network, and is being conducted in conjunction with collaborators at Monash University, the Royal Melbourne Hospital and the University of Freiburg.
These are grouped by topic area.
* indicates corresponding author
** indicates joint first author
Xu JY, O’Connell MA, Notini L, Cheung AS, Zwickl S, Pang KC*. (2021) Selective estrogen receptor modulators (SERMs): a potential option for non-binary gender-affirming hormonal care? Frontiers in Endocrinology.
Lai TC, Davies C, Robinson K, Feldman D, Elder CV, Cooper C, Pang KC*, McDougall R*. (2021) Effective fertility counselling for transgender adolescents: a qualitative study of clinician attitudes and practices. BMJ Open.11(5):e043237.
Bloom T, Nguyen TP, Lami F, Pace C, Poulakis Z, Telfer M, Taylor A, Pang KC*, Tollit MA*. (2021) Measurement tools for gender identity, gender expression and gender dysphoria in transgender and gender diverse children and adolescents: a systematic review. Lancet Child and Adolescent Health. S2352-4642(21)00098-5.
McPhate L, Williams K, Winther J, Vance A, Pang KC*, May T (2021). Gender Variance in Children and Adolescents with Neurodevelopmental and Psychiatric Conditions from Australia. Archives of Sexual Behaviour. 50(3):863-871.
Pang KC*, de Graaf NM, Chew D, Hoq M, Keith DR, Carmichael P, & Steensma TD. (2020) Association of media coverage of transgender and gender diverse issues with rates of referral of transgender children and adolescents to specialist gender clinics in the UK and Australia. JAMA Network Open. 3(7):e2011161.
Lai TC, McDougall R, Feldman D, Elder CV, Pang KC*. (2020) Fertility Counselling for Transgender Adolescents: a review. Journal of Adolescent Health. 66(6): 658-665
Pang KC*, Peri AJS, Chung HE, Telfer M, Elder CV, Grover S, Jayasinghe Y. (2020) Rates of Fertility Preservation Use Among Transgender Adolescents. JAMA Pediatrics. 13;e200264..
Chew D, Tollit MA Poulakis Z, Zwickl S, Cheung AS, Pang KC*. (2020) Youths with a non-binary gender identity: a review of their sociodemographic and clinical profile. Lancet Child and Adolescent Health. pii: S2352-4642(19)30403-1.
Pang KC, Notini L, McDougall R, Gillam L, Savulescu J, Wilkinson D, Clark BA, Olson-Kennedy J, Telfer MM, Lantos JD. (2020) Ethics Rounds: Long-term puberty suppression for a non-binary teen. Pediatrics. 145(2). pii: e20191606.
Ferguson G, Simm P, O’Connell M, Pang KC*. (2019) Use of puberty blockers in trans and gender diverse adolescents frequently results in loss of bone mineral density. BMJ. 367:l6471
Tollit MA, Pace CC, Telfer MM, Hoq M, Bryson J, Cooper C, Fulkoski N, Pang KC*. (2019) What are the health outcomes of trans and gender diverse young people in Australia? Study protocol for the Trans20 longitudinal cohort study. BMJ Open. 9:e032151. doi: 10.1136/bmjopen-2019-032151
Pang KC*, Telfer MM, Tollit MA, Pace CC. (2019). Everyone agrees transgender children require more science. Medical Journal of Australia. doi: 10.5694/mja2.50237
Notini L, McDougall R, Pang KC*. (2019) Should parental refusal of puberty-blocking treatment be overridden? The role of the harm principle. American Journal of Bioethics. 19(2):69-72.
Notini L, Gillam, Pang KC*. (2018) Facial feminization surgery: Personal identity, compensatory justice and resource allocation. American Journal of Bioethics. 18(12): 12-5.
Pang KC*, Feldman D, Oertel R, Telfer M. (2018) Molecular karyotyping in children and adolescents with gender dysphoria. Transgender Health. 3(1): 147–153.
Telfer MM, Tollit MA, Pace CC, Pang KC*. (2018) Australian Standards of Care and Treatment Guidelines for Trans and Gender Diverse Children and Adolescents. Medical Journal of Australia. 209(3):132-136
Chew D, Anderson J, Williams K, May T, Pang KC*. (2018) Hormonal Treatment in Young People with Gender Dysphoria: a systematic review. Pediatrics. 141(4): pii: e20173742
Immunology and genetics
Foers AD, Garnham AL, Chatfield S, Smyth GK, Cheng L, Hill AF, Wicks IP, Pang KC*. Extracellular Vesicles in Synovial Fluid from Rheumatoid Arthritis Patients Contain miRNAs with Capacity to Modulate Inflammation. Int J Mol Sci. 2021 May 6;22(9):4910.
Smith BRC, Nyström A, Nowell CJ, Hausser I, Gretzmeier C, Robertson SJ, Varigos GA, Has C, Kern JS*, Pang KC*. Mouse models for dominant dystrophic epidermolysis bullosa carrying common human point mutations recapitulate the human disease. Dis Model Mech. 2021 Jun1; 14(6):dmm048082.
Nguyen TA, Smith BRC, Belz GT, Barrios MH, Elgass KD, Weisman WA, Preston S, Lundie R, Pellegrini M, O’Keeffe M, Wicks IP, Masters SL, Hunter CP*, Pang KC*. (2017) Sidt2 transports extracellular dsRNA into the cytoplasm for innate immune recognition. Immunity 47: 498-509.
Foers AD, Dagley LF, Chatfield S, Webb AI, Cheng L, Hill AF, Wicks IP, Pang KC*. Proteomic analysis of extracellular vesicles reveals an immunogenic cargo in rheumatoid arthritis synovial fluid. Clin Transl Immunology. 2020 Nov 7;9(11):e1185.
Foers AD, Garnham AL, Smyth GK, Proudman SM, Cheng L, Hill AF, Pang KC*, Wicks IP*. Circulating Small Noncoding RNA Biomarkers of Response to Triple Disease-modifying Antirheumatic Drug Therapy in White Women With Early Rheumatoid Arthritis. J Rheumatol. 2020 Dec 1;47(12):1746-1751. doi: 10.3899/jrheum.191012.
Nguyen TA, Smith BRC, Elgass KD, Creed SJ, Cheung S, Tate MD, Belz GT, Wicks IP, Masters SL, Pang KC*. SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm. J Immunol. 2019 Jun 15;202(12):3483-3492.
Nguyen TA, Bieging-Rolett KT, Putoczki TL, Wicks IP, Attardi LD, Pang KC*. SIDT2 RNA Transporter Promotes Lung and Gastrointestinal Tumor Development. iScience. 2019 Oct 25;20:14-24.
As lead investigator, Ken has attracted >$4.0 million in research funding from various government, philanthropic and professional bodies, including the NHMRC, RACP, Royal Children’s Hospital Foundation, Hugh Williamson Foundation Trust, Australian-American Fulbright Commission, American Australian Association, Menzies Foundation, DEBRA Australia and CASS Foundation.