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Dr Melissa Lee
Dr Melissa Lee is an early career clinician-researcher working full-time clinically as a Cardiology registrar at the Royal Melbourne Hospital. She holds honorary appointments as an Honorary Fellow at the Murdoch Children's Research Institute (MCRI) and as an Honorary Senior Fellow at the Department of Paediatrics and at the Department of Medicine (RMH), University of Melbourne. She has a strong interest in adult congenital heart disease in both clinical and academic respects. Her current main research focus is in aortic arch obstruction, particularly, coarctation of the aorta. She leads a long and in-depth line of research into improving the long-term outcomes of patients with aortic arch obstruction.
- 2021-2025: Investigator Grant: Medical Research Future Fund (MRFF)
- 2020: Premier's Award for Health and Medical Research - Winner (Clinical Researcher)
- 2017: National Health and Medical Research Council (NHMRC) 'Medical Research Postgraduate Scholarship'
- 2017: Heart Foundation 'Collaboration and Exchange Award'
- 2016: 'The Henry and Rachel Ackman Travelling Scholarship', Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne.
- 2015: Heart Foundation 'Health Professional Scholarship'
- 2015: Heart Foundation 'Noel and Imelda Foster Research Award'
- 2014: Avant Mutual Group 'Doctors in Training Research Scholarship (part-time)'
Dr Melissa Lee's research is centred on the long-term outcomes of patients with congenital heart disease. She is experienced in retrospective and prospective cohort studies. Her PhD examined the long-term outcomes after surgical repair of coarctation with a particular emphasis on hypertension. Her research has directly led to change in the clinical management of this patient population. She has also led the establishment of the Aortic Arch Biobank at MCRI to further evaluate the genetics of aortic arch conditions.
She has over 30 articles peer-review publications and textbook chapters and presented extensively at international and national conferences.
She has been awarded multiple awards and scholarships for her research including a Medical Research Future Fund (MRFF) Investigator grant (2021-2025); 2020 Premier's Award for Health and Medical Research (Winner - Clinical Researcher); National Health and Medical Research Council (NHMRC) Medical Research Postgraduate Scholarship; Heart Foundation Health Professional Scholarship, Collaboration and Exchange Award, and the Noel and Imelda Foster Research Award; University of Melbourne; and Avant. Her research has attracted grant funding from MRFF, HeartKids, and MCRI.
She has successfully co-supervised 8 MD Research Project (MDRP) research students in the Doctor of Medicine at the University of Melbourne.
Lee MGY, Babu-Narayan SV, Kempny A, Uebing A, Montanaro C, Shore DF, d'Udekem Y, Gatzoulis MA. Long-term mortality and cardiovascular burden for adult survivors of coarctation of the aorta. Heart. 2019 Aug;105(15):1190-1196.
Lee MGY, Millar J, Rose E, Jones A, Wood D, Luitingh TL, Zannino D, Brink J, Konstantinov IE, Brizard CP, d'Udekem Y. Laryngeal ultrasound detects a high incidence of vocal cord paresis after aortic arch repair in neonates and young children. Journal of Thoracic and Cardiovascular Surgery. 2018 Jun;155(6):2579-2587.
Lee MGY, Hemmes RA, Mynard J, Lambert E, Head GA, Cheung MMH, Konstantinov IE, Brizard CP, Lambert G, d'Udekem Y. Elevated sympathetic activity, endothelial dysfunction, and late hypertension after repair of coarctation of the aorta. International Journal of Cardiology. 2017 Sep 15;243:185-190.
Lee MGY, Allen SL, Kawasaki R, Kotevski A, Koleff J, Kowalski R, Cheung MMH, Konstantinov IE, Brizard CP, d'Udekem Y. High prevalence of hypertension and end-organ damage late after coarctation repair in normal arches. Annals of Thoracic Surgery. 2015 Aug;100(2):647-53.
Lee MGY, Kowalski R, Galati JC, Cheung MM, Jones B, Koleff J, d'Udekem Y. Twenty-four-hour ambulatory blood pressure monitoring detects a high prevalence of hypertension late after coarctation repair in patients with hypoplastic arches. Journal of Thoracic and Cardiovascular Surgery. 2012 Nov;144(5):1110-6.
Lee MGY, Brink J, Galati JC, Rakhra SS, Konstantinov IE, Cheung MH, Brizard CP, d'Udekem Y. End-to-side repair for aortic arch lesions offers excellent chances of reaching adulthood without reoperation. Annals of Thoracic Surgery. 2014 Oct;98(4):1405-11.
- 2021-2025: Investigator Grant: Medical Research Future Fund (MRFF) Priority Round
- 2014, 2015, 2017: HeartKids 'Grants-in-Aid'
- 2012: MCRI CCN Theme grant