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Dr Tom Forbes
Tom is a Consultant General Paediatrician and Paediatric Nephrologist. He completed his undergraduate medical degree with Monash University in 2005 and trained in paediatrics at the Royal Children's Hospital (Melbourne) between 2007 and 2010. Tom moved to the UK in 2010 with his wife who had secured a post-doctoral fellowship at The University of Cambridge. During his time in the UK Tom worked as a paediatric nephrology registrar at Birmingham Children's Hospital and Nottingham University Hospitals Queen's Medical Centre. He also completed a Post-Graduate Award in the Management of Chronic Kidney Disease with the University of Warwick in Coventry.
Tom returned to Melbourne in 2013 and completed a paediatric nephrology fellowship at the Royal Children's Hospital. He became a Fellow of the Royal Australasian College of Physicians in 2015.
Consultant Paediatric Nephrologist, Royal Children's Hospital, Melbourne
PhD Candidate, University of Melbourne
Member of the Australian and New Zealand Paediatric Nephrology Association
Member of the International Pediatric Nephrology Association
Member of the Australian and New Zealand Society of Nephrology
KIDGEN Renal Genetic Consortium
- Australian Society for Stem Cell Research/Australian Cell and Gene Therapy ASM - Best PhD Oral Presentation (May 2017)
- Poster Award - Kidgen Renal Genetics Symposium (Nov 2017)
- International Society for Stem Cell Research Travel Award (June 2018)
- Best 3rd Year PhD Poster – Melbourne Children's Campus Research Students Association Student Symposium (Nov 2018)
Tom's PhD examines the capabilities and limitations of kidney organoids as inherited renal disease models. He differentiates iPSC from patients with genetic kidney disease and examines the organoids for evidence of the renal disease and possibilities for their use as a screening platform for novel therapeutics.
Phipson B, Er PX, Combes AN, Forbes TA, Howden SE, Zappia L, Yen HJ, Lawlor KT, Hale LJ, Sun J, Wolvetang E, Takasato M, Oshlack A, Little MH. Nature Methods. 2019;16:79-87 https://doi.org/10.1038/s41592-018-0253-2
Little MH, Kumar SV, Forbes TA. Recapitulating kidney development: Progress and challenges. Semin Cell Dev Biol. 2018. pii:S1084-9521(17)30426-3. doi: 10.1016/j.semcdb.2018.08.015.
Forbes TA, Howden SE, Phipson B, Maksimovic J, Hale L, Wilson S, Quinlan C, Ho G, Holman K, Bennetts B, Crawford J, Trnka P, Oshlack A, Patel C, Mallett A, Simons C, Little MH. Patient-iPSC-Derived Kidney Organoids Show Functional Validation or a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms. Am J Human Genet. 2018; 102(5):816-31 https://doi.org/10.1016/j.ajhg.2018.03.014
Little M.H., Takasato M., Soo J.YC., Forbes T.A. (2017) Recapitulating Development to Generate Kidney Organoid Cultures. In: Tsuji T. (eds) Organ Regeneration Based on Developmental Biology. Springer, Singapore https://doi.org/10.1007/978-981-10-3768-9_11
Lunn AJ & Forbes TA. Haematuria and proteinuria in childhood. Pediatr Child Health. 2016;26(8):321-7 doi: http://dx.doi.org/10.1016/j.paed.2016.04.002
Forbes TA, McMinn A, Crawford N, Leask, J, Danchin M. Vaccination uptake by vaccine-hesitant parents attending a specialist immunization clinic in Australia. Hum Vacc Immunother. 2015;11(12):2895-903 doi: 10.1080/21645515.2015.107099
Lee S, Forbes TA. Heads Up: Azithromycin is associated with increased risk of pyloric stenosis in infants. J Paediatr Child Health. 2015:51(9):939 doi: 10.1111/jpc.12966
Forbes TA, Watson AR, Zurowska A et al. Adherence to transition guidelines in European paediatric nephrology units. Pediatr Nephrol. 2014;29(9):1617-24 DOI: 10.1007/s00467-014-2809-4
Forbes TA, Lunn A. Montelukast: a novel therapeutic option in eosinophilic peritonitis Pediatr Nephrol. 2014;29(7):1279-82 DOI: 10.1007/s00467-013-2718-y
Forbes TA, Bradbury MG, Goodship THJ, McKiernan PJ, Milford DV. Changing strategies for organ transplantation in atypical haemolytic uraemic syndrome: a tertiary case series. Pediatr Transplant. 2013; 17(3): E93-E99. DOI: 10.1111/petr.12066
Lunn A, Forbes TA. Haematuria and proteinuria in childhood. Pediatr Child Health. 2012; 22(8): 315-321. DOI: 10.1016/j.paed.2012.02.011
Forbes T, O'Donnell R. Anaphylactoid reaction to facial adder bite. Arch Dis Child. 2011; 96(9): 822. DOI: 10.1136/archdischild-2011-300240
Forbes T, Goeman E, Stark Z, Hynson J, Forrester M. Discussing withdrawing and withholding of life-sustaining medical treatment in a tertiary paediatric hospital: A survey of clinician attitudes and practices. J Paediatr Child Health. 2008; 44: 392-398. DOI: 10.1111/j.1440-1754.2008.01351.x
NHMRC Post-Graduate Scholarship - 2016
RACP Jacquot Award for Excellence - 2016