White matter disorders at MCRI

The Australian Leukodystrophy Clinical and Research Program at the Murdoch Children's Research Institute (MCRI) is dedicated to improving diagnoses, experiences, and outcomes for families affected by leukodystrophies and white matter disorders. Our program encompasses a range of research studies, including patient registries, natural history studies, and clinical trials for specific leukodystrophies.

Our mission

With our White Matter Disorders clinic at The Royal Children’s Hospital and innovative research programs, our mission is to ensure that every family affected by leukodystrophy has the support and resources needed to navigate the various diagnostic and therapeutic options available.

Research initiatives

• Patient registry: Collecting comprehensive data to better understand leukodystrophies and white matter disorders.
• Natural history studies: Tracking the progression of these conditions over time to identify patterns and potential interventions.
• Clinical trials: Testing new treatments and therapies to find effective solutions for specific leukodystrophies.
  
  

Collaborations and support

Our program is a collaboration between leading medical research institutes, hospitals, and universities across Australia, including The Royal Children’s Hospital, the University of Queensland, the University of New South Wales, and the Women’s and Children’s Hospital in South Australia. We also work closely with international experts through the Global Leukodystrophy Initiative.

The advocacy of the Damiani family and the Mission Massimo Foundation has been instrumental in making this program possible. It is funded through the Australian Federal Government Medical Research Future Fund (MRFF) and is administered by Australian Genomics.

For more information visit the Australian Leukodystrophy Clinical and Research Program.

Join our research program

We invite children and adults with a diagnosed or undiagnosed leukodystrophy or white matter disorder living in Australia to participate in our research studies. By joining our program, you can contribute to advancing our understanding and treatment of these conditions.

Who Can Take Part?

• Children and adults with a leukodystrophy or white matter disorder
• Residents of Australia