Bruce Lefroy Centre (BLC)

Generating knowledge that improves the lives of individuals, families and communities affected by genetic disorders

Established in 2003, the Bruce Lefroy Centre (BLC) at the Murdoch Children’s Research Institute is dedicated to advancing research into genetic conditions.

Named in honour of Bruce Lefroy, the Centre was founded through the generosity of the Lefroy family and their supporters.

Our research focus

The Centre has a focus on:

• research into genetic diseases that affect the nervous system
• research into genetic testing
• ethics in clinical genetics
• the study of genetic syndromes
  
  

Key areas of research

We specialise in two key areas of genetic research:

• Genetic Health: Investigating inherited conditions such as Friedreich ataxia, haemochromatosis and Huntington disease. Our work also explores the ethical, social and clinical aspects of genetic testing.
• Neurogenetics: Studying neurodevelopmental and neurogenetic disorders including autism, brain malformations, Parkinson’s disease and various forms of ataxia.

Read more about our research below.

Our impact - transforming diagnosis and treatment

Our researchers have contributed to major discoveries that are shaping the future of genetic medicine that are advancing the diagnosis and treatment of genetic conditions such as ataxia, brain malformations, Friedreich ataxia, and haemochromatosis.

These breakthroughs are helping us:

• Diagnose conditions more quickly and accurately
• Develop innovative and targeted treatments
• Provide more comprehensive and personalised counselling to families.

Throughout its history, the centre has launched several ground-breaking studies and has contributed to worldwide knowledge of genetics, helping countless children and their families, with projects including:

• The Accelerated Gene Identification Program, which has fast-tracked diagnosis for rare condition
• Development of new treatments and improved counselling for families affected by genetic disorders
• Global collaborations that enhance our understanding of complex genetic syndromes.

Leadership and collaboration

The Centre is co-directed by Professor Martin Delatycki and Professor Paul Lockhart, both internationally recognised leaders in clinical genetics and molecular research.

We work closely with clinicians, scientists and community groups to ensure our research translates into real-world benefits.

Watch how donor support helped build the Bruce Lefroy Centre

Contact us

Professor Paul Lockhart, Group Leader / Co-Director BLC
Email:  show email address

Professor Martin Delatycki, Group Leader / Co-Director BLC
Email: [email protected]