SAEFVIC

SAEFVIC (Surveillance of Adverse Events Following Vaccination In the Community) is a public health partnership initiative of the Victorian Immunisation Program funded by the Department of Health, Victoria. It was established in 2007 and is based at the Murdoch Children's Research Institute.

SAEFVIC is a vaccine safety service and clinical immunisation research team, focusing on adverse events following immunisation (AEFI), vaccine-preventable disease research as well as immunisation education.

The initiative is a national leader in vaccine safety, with the SAEFVIC team comprising of immunisation nurses, administrative staff, an epidemiologist, data manager, research staff and clinicians.  It is a specialist vaccine safety service that helps immunisation providers report and manage both children and adults who have had an AEFI. Our clinical services are based at The Royal Children's Hospital (Parkville) and Monash Health (Clayton) It also provides regional clinical support via TeleHealth. Any trends in reports are notified and investigated quickly in close liaison with Victorian and National Health Authorities.

SAEFVIC clinical research includes surveillance and drug trials.  Surveillance projects include active and passive studies, including involvement in national collaborative networks. This includes annual influenza vaccine safety surveillance (AusVaxSafety), and hospital-based active surveillance of childhood conditions of public health importance through PAEDS (Paediatric Active Enhanced Surveillance). We also have National Health and Medical Research Centre (NHMRC)-funded projects, including vaccine safety research into febrile seizures and special risk groups, and response to pneumococcal vaccines in asplenic patients.

Group Members: 
A/Prof Jim Buttery
Role: 
Group Leader
Georgina Lewis
Role: 
Clinical Manager
Hazel Clothier
Role: 
Epidemiologist
Alissa McMinn
Role: 
Research Nurse Manager
Annette Alafaci
Role: 
Research Assistant
Donna Lee
Role: 
Research Nurse
Gowri Selvaraj
Role: 
Research Assistant
Leonie Hickie
Role: 
Research Nurse
Margie Gibson
Role: 
Research Nurse
Mee Lee Easton
Role: 
Statistician
Victoria Scott
Role: 
Administrative Assistant
Peta Kilsby
Role: 
Research Nurse
Thao Nguyen
Role: 
Data Manager
Vick Wilby
Role: 
Administrative Assistant
Lois Tham
Role: 
Administrative Assistant
Anna Bourke
Role: 
Research Nurse
Kate Brownlee
Role: 
Research Nurse
Adele Harris
Role: 
Research Nurse
Jock Lawrie
Role: 
Statistician
Mel Addison
Role: 
Research Nurse
Rachael McGuire
Role: 
Education Nurse Coordinator
RCH Medical Staff Immunisation
Dr Margie Danchin
Role: 
Paediatrician
Dr Kirsten Perrett
Role: 
Paediatrician
Dr Teresa Lazzaro
Role: 
Paediatrician
Dr Daniel Golshevsky
Role: 
Paediatrician
Dr Fiona Russell
Role: 
Paediatrician
Dr Jane Standish
Role: 
Paediatrician
Monash Health Medical staff AE
Dr Tony Korman
Role: 
Director, Monash Infectious Diseases
Dr Dave Burgner
Role: 
Paediatric Infectious Diseases consultant
Dr Michelle Giles
Role: 
Infectious Diseases Physician
Dr Samar Ojaimi
Role: 
Infectious Disease Physician

The Melbourne Vaccine Education Centre (MVEC)
MVEC was launched in February 2014. SAEFVIC is a national leader in vaccine education and this project is a collaboration between the Melbourne Children’s campus and Monash Health.

AusVaxSafety
AusVaxSafety is a national enhanced surveillance system to monitor adverse events following immunisation with influenza vaccine in children under five years of age. The Victorian vaccine safety surveillance is coordinated by SAEFVIC. The AusVaxSafety team are using Vaxtracker, a technological monitoring system where the parents/carers of children who have received influenza vaccine as part of good clinical care are offered participation and following consent, parents/carers are sent an SMS message or email three days after vaccination. They are asked to provide information on whether their child experienced any adverse event after vaccination. Each week, data from all parent/carer reports are combined and analysed. Surveillance under AusVaxSafety commenced in March 2014 and up-to-date results on this important vaccine safety initiative are detailed on the website.

AEFI-CAN (Adverse event following immunisation- clinical assessment network)
SAEFVIC is the coordinating centre for this Department of Health funded network currently focusing on HPV adverse events.

PAEDS (Paediatric Active Enhanced Disease Surveillance)
This study uses hospital-based active surveillance to identifying and investigate childhood conditions of public health importance, which are difficult to adequately capture through other surveillance mechanisms. Conditions of interest include: acute flaccid paralysis, encephalitis, intussusception, pertussis and varicella.

PAPI (Protecting asplenic children and adults against pneumococcal disease and identifying optimal immunisation regimens)
This is a multi-centre Phase IV study conducted at MCRI/RCH, Monash Medical Centre, and the Alfred Hospital, supported by an NHMRC project grant.

Febrile Seizures Following vaccination in children: What is the long term clinical and developmental outcome?
This is multi-centre NHMRC funded project conducted at Murdoch Children's and The Royal Children's Hospital; The Epilepsy Research Centre, VIC; The Children’s Hospital at Westmead, NSW; Women’s and Children’s Hospital, SA; Princess Margaret Hospital, WA.