Heart Regeneration

Research area:  Stem cell biology

Our vision is to transform the treatment of childhood heart disease using stem cell technologies.

Frontline therapies for childhood heart disease have not changed in over 30 years. The Heart Regeneration and Heart Disease Team aims to transform the treatment of childhood heart disease using stem cell technologies.

Our laboratory harnesses the power of pluripotent stem cells to create human models of disease as a platform for therapeutic development. Our research pipeline spans the full spectrum from the operating theatre to the single cell, taking full advantage of the unique capacity of the Melbourne Children’s campus.

The Team are generating heart organoids from patient stem cells, which can investigate genetic causes of childhood heart disease in patients, as well as to screen for drugs that damage or regenerate heart tissue.

Finally, we are also harnessing the regenerative potential of stem cells to create bioengineered heart tissue to treat heart failure in children.

Contact us

Adam Piers
Program Manager for Heart Failure Flagship and CardioRegen

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